There are around 1200 registered independent and institutional ethics committees. All registered ethics committees have to go through accreditation process which was introduced recently by NABH and responsibility is assigned to quality council of India (QCI) to accredit all registered ethics committees in India. The ethics committee should review and accord its approval to a clinical trial as per Schedule Y, the Good Clinical Practice Guidelines for Clinical Trials in India and other applicable regulatory requirements for safeguarding rights, safety and well-being of the trial subjects. The applications of registration of Ethics Committee have to be mandatorily filed online by www.cdscoonline.gov.in.